Instructions for setting up Adobe Acrobat Reader for digital signing Reference num. 4056 Views: 2109 Home / FAQ / Instructions for setting up Adobe Acrobat Reader for digital signing Before digitally signing a pdf document, you must adjust the settings in Adobe Acrobat Reader as follows: 1 Open Adobe Acrobat Reader. Select “Edit” at the top and then “Preferences…” at the bottom. 2 Select “Security (Enhanced)”. Uncheck “Enable Protected Mode at startup” and “Enable Enhanced Security”. Confirm by clicking on “OK”. 3 Now the program needs to be closed. Select “File” at the top and “Exit Application” at the bottom of the list.